Which statement about clonidine–related constipation is correct, and how can it be addressed?

• A. Constipation is unrelated to clonidine; no dietary change is needed.
• B. Constipation is a common side effect and increasing fluid and fiber helps prevent it.
• C. Constipation is best treated with increased caffeine intake.
• D. Constipation is an emergency symptom requiring immediate hospital care.

Answer: (B)

Constipation from clonidine happens because this drug can slow gastrointestinal motility, so this side effect is common and expected. The best way to address it is with preventative, nonpharmacologic strategies: drink more fluids and increase dietary fiber to soften stools and promote regular bowel movements. If the stool remains hard or difficult to pass, a clinician may add a stool-softener or an osmotic laxative as needed. Relying on caffeine as a treatment isn’t appropriate for clonidine-related constipation, and this symptom is not an emergency requiring hospital care. If constipation is persistent or severe, the healthcare provider may consider adjusting the clonidine dose or exploring other management options.