What instruction should the nurse provide to the client who needs to apply nitroglycerin ointment?

• A. Use the fingers to spread the ointment evenly over a 3-inch area.
• B. Apply the ointment to a nonhairy part of the upper torso.
• C. Massage the ointment into the skin.
• D. Cover the application paper with ointment before use.

Answer: (B)

Nitroglycerin ointment is a transdermal medication, so how you apply it affects how much drug gets absorbed and how the skin responds. The correct instruction is to place a thin, uniform layer on a clean, dry, nonhairy area of the upper chest or back. This site choice supports consistent absorption and minimizes skin irritation from hair or friction. It’s important not to rub the ointment into the skin or massaged it in, because rubbing can increase absorption and cause sudden drops in blood pressure. The dose is typically applied using a dosing paper placed on the skin, not spread by the fingers, and you should avoid applying to hairy areas to prevent inconsistent absorption. After applying, rotate sites to protect the skin, and follow any additional directions about cleaning the area and washing hands to prevent accidental exposure to others.